Glucocorticoid Regulation of Prolactin Receptors on Mammary Cells in Culture*
- 1 May 1979
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 104 (5) , 1447-1449
- https://doi.org/10.1210/endo-104-5-1447
Abstract
Mouse mammary epithelial cultures were examined for the ability to specifically bind [125I]PRL after cultivation on floating collagen gels. Corticosterone, particularly hydrocortisone, were effective in increasing the ability of mouse mammary cells to bind [125I]PRL. The absence of a glucocorticoid in the medium resulted in a loss of PRL binding during the 3 days in culture. 17β-Estradiol, progesterone, and aldosterone at equal molar concentration had no or only a small effect in increasing [125I]PRL binding.Keywords
This publication has 1 reference indexed in Scilit:
- Induction of a Lactogenic Receptor in Rat Liver: Influence of Estrogen and the PituitaryProceedings of the National Academy of Sciences, 1974