Seven-Year Remission in an Adult with Acute Leukemia

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Abstract
ACUTE leukemia has usually been considered a rapidly fatal disease, but with the advent of antimetabolites and corticosteroid therapy, lengthy remissions have frequently been reported, particularly in childhood.1 , 2 In some cases repeated remissions have been obtained by a change from one antimetabolite to another, or by the judicious use of large-dose corticosteroid therapy.3 4 5 There can be no question now that definite prolongation of life-span has been achieved. However, in acute leukemia in adults, prolonged remissions with antimetabolite therapy have been unusual, and survival beyond a year, and even more so beyond two years, is exceptional.6 , 7 The purpose of this communication . . .