Increased frequency of HLA-DRwl4b(w6)-associated RFLP in Greenlanders of Eskimo origin
- 1 March 1991
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 37 (3) , 127-129
- https://doi.org/10.1111/j.1399-0039.1991.tb01857.x
Abstract
HLA-DR typing by the restriction fragment length polymorphism (RFLP) technique of 42 Greenlanders living in northern Jutland, Denmark, revealed a phenotype frequency of 33.3% for HLA-DRw14b(w6), which is significantly different from the frequency of 0.0% observed among 98 Danes of Caucasian origin. When comparing the two populations, the frequency of other HLA-DRB allogenotypes show insignificant variations. Since HLA-DRw14b(w6) is carried by approximately one-third of the Greenlanders tested, this allogenotype may serve as a useful marker in further anthropological and immunogenetic studies.Keywords
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