Effect of Alimentary Lipemia on the Turnover of Plasma Phosphatides in the Dog

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Abstract
Lymph P32-labeled phospholipides are removed from the blood only slightly more rapidly than plasma phospholipides. The observation that lymph and plasma phospholipides exchange rapidly when mixed in vitro may explain this similarity. The amount of phospholipide which is contributed to plasma by lymph during alimentary lipemia entirely explains the 15–30% increase in plasma phosphatide concentration in fat-fed dogs. Alimentary lipemia in dogs does not appear to increase the disappearance of injected labeled plasma phosphatides from the blood or the synthesis of hepatic and intestinal phospholipides. Thus, no evidence was obtained for an increase in the turnover of plasma phosphatides during transport of dietary fat in the bloodstream.