Relationship between oestrogen-receptor content and histological grade in human primary breast tumours
Open Access
- 1 December 1978
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 38 (6) , 745-748
- https://doi.org/10.1038/bjc.1978.282
Abstract
A series of 300 patients presenting consecutively with primary operable breast cancer has been studied. A significant correlation was found between oestrogen-receptor (ER) content and histological grade: the better-differentiated tumours rarely lacked receptor. This correlation was significant only in women defined as post-menopausal. Data on early recurrence of disease indicate a worse prognosis for women in whom primary tumours are ER-.Keywords
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