APP Gene Promoter Constructs Are Preferentially Expressed in the CNS and Testis of Transgenic Mice
- 26 November 1997
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 240 (3) , 759-762
- https://doi.org/10.1006/bbrc.1997.7728
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's diseaseNature Medicine, 1996
- Nuclear and Cytoplasmic Localization of the β-Amyloid Peptide (1–43) in Transfected 293 CellsBiochemical and Biophysical Research Communications, 1996
- Therapeutic Approaches Related to Amyloid-.beta. Peptide and Alzheimer's DiseaseJournal of Medicinal Chemistry, 1995
- Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1Molecular Brain Research, 1995
- A direct role for protein kinase C and the transcription factor Jun/AP-1 in the regulation of the Alzheimer's beta-amyloid precursor protein gene.Journal of Biological Chemistry, 1994
- Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain.Proceedings of the National Academy of Sciences, 1992
- A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N–terminus of β–amyloidNature Genetics, 1992
- Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's diseaseNature, 1991
- Expression of the Alzheimer amyloid precursor gene transcripts in the human brainNeuron, 1988
- CELLULAR LOCALIZATION OF MESSENGER RNA ENCODING AMYLOID-BETA-PROTEIN IN NORMAL TISSUE AND IN ALZHEIMER DISEASEAlzheimer Disease & Associated Disorders, 1988