Studies on the Hormone-sensitive Lipase of Rat Epididmal Adipose Tissue

Publisher Website
Google Scholar
Abstract
Activity of rat epididymal adipose tissue lipase was significantly influenced according to the way of its expression. When the activity was expressed as μEq per g of tissue, the lipase activity of the tissue of starved rats was higher than that of the tissue of fed rats. On the other hand, when expressed as μEq per mg of protein, the lipase activity of starved rats was lower than that of the tissue of fed rats. Though adrenaline increased the release of free fatty acids from adipose tissue slice, the lipase activity was not activated by this hormone. Our cell free system, in which adrenaline stimulated lipolysis, was compared with Rizack‘s system. Though remarkable activation was observed in our system, there was no significant stimulation of lipolysis by adrenaline in Rizack’s system. Dichloroisoprotercnol considerably inhibited the stimulation of lipolysis by adrenaline in our cell free system as well as in the slice system. These results support our previous conclusion that there is no hormone-sensitive lipase in adipose tissue.

This publication has 0 references indexed in Scilit: