CIRCADIAN DRINKING PATTERN OF SARDINIAN ALCOHOL-PREFERRING RATS
Open Access
- 1 July 1996
- journal article
- research article
- Published by Oxford University Press (OUP) in Alcohol and Alcoholism
- Vol. 31 (4) , 385-388
- https://doi.org/10.1093/oxfordjournals.alcalc.a008166
Abstract
The present study was designed to assess the temporal pattern of ethanol intake over a 24 h period in selectively bred, Sardinian alcohol-preferring (sP) rats Ethanol intake occurred under the two-bottle, free choice regimen. sP rats consumed ethanol in three distinct peaks, rather regularly distributed over the 12 h dark phase of the light-dark cycle and positively correlated with food intake episodes. The temporal distribution of ethanol intake and estimated blood alcohol levels are consistent with the hypothesis that sP rats voluntarily drink ethanol for its pharmacological effectsKeywords
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