Resin-to-resin Petasis borono-Mannich reaction between dialkylamino resins and supported boronic acids

Abstract
Iminium intermediates, formed from the condensation of glyoxylic acid and resins functionalized with a secondary amine, are coupled to boronic acids transferred to solution from the corresponding [N,N-diethanolaminomethyl polystyryl boronates by in situ transesterification with the ethanol co-solvent to provide arylglycine derivatives.

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