A basis for utlization of unnatural pentoses and pentitols by Aerobacter aerogenes.

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Abstract
Two RNA replicases induced in the same host by unrelated RNA bacteriophages were purified and their responses to various RNA molecules examined. Both are virtually inactive with heterologous RNA, including ribosomal and sRNA of the host under optimal ionic conditions. Neither replicase can function with the other''s RNA. Each recognizes the RNA genome of its origin and requires it as a template for synthetic activity. This selectivity of its replicase is of obvious advantage to a virus attempting to direct its own duplication in a cellular environment replete with other RNA molecules.