• 1 January 1966
    • journal article
    • Vol. 1  (1) , 45-60
Abstract
A nephrotic syndrome was induced in randomly bred Sprague-Dawley rats by repeated intraperitoneal injections of homologous kidney extract and Freund's complete adjuvant. Cell injury in vitro was measured by estimating the release of radioactivity from damaged target cells labelled with 14C-thymidine. Various conditions influencing the reproducibility of the isotope method were investigated.