Ovarian Follicular Development during the Rat Estrous Cycle: Gonadotropin Receptors and Follicular Responsiveness1
- 1 June 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 20 (5) , 1159-1165
- https://doi.org/10.1095/biolreprod20.5.1159
Abstract
The LH and FSH receptor content in thecal and granulosa cells of large antral follicles was measured by in vitro binding assays and in vivo autoradiography during the rat estrous cycle. Specific binding of [125I]-hCG to granulosa cells increased from 125I]-hFSH to granulosa cells was consistently between 2000 and 3000 cpm/µg DNA throughout the cycle. Specific hCG binding to thecal cells also increased between diestrus and proestrus, while specific hFSH binding to thecal cells was essentially nondetectable.This publication has 3 references indexed in Scilit:
- Hormonal Control of 17β-Estradiol Biosynthesis in Proestrous Rat Follicles: Estradiol Production by Isolated Theca Versus Granulosa*Endocrinology, 1978
- Androgen Production by Theca and Granulosa Isolated from Proestrous Rat Follicles1Endocrinology, 1977
- The Porcine Ovarian Follicle: III. Development of Chorionic Gonadotropin Receptors Associated with Increase in Adenyl Cyclase Activity During Follicle MaturationEndocrinology, 1976