Pubertal Endocrinology of the Baboon: Elevated Somatomedin-C/Insulin-Like Growth Factor I at Puberty

Publisher Website
Google Scholar
Abstract
Previous data suggested an increase in the rate of weight gain and linear growth in the baboon between 3 and 4yr of age, similar to the pubertal growth spurt in man.In thiscross-sectional study, radioimmunoassayable concentrations of somatomedin-C/insulin-like growth factor I (SM-C/IGF-I) were compared in prepubertal (>10 yr) animals. SM-C/IGF-I concentrations in prepubertalmales (0.97 ± 0.10 U/ml) were low and were not different fromthose in prepubertal females (0.98 ± 0.15 U/ml). Between 3 and4 yr, SM-C/IGF-I increased significantly in both sexes (8.87 ± 0.74 and 5.27 ± 0.52 U/ml, male and female, respectively) anddecreased (5.92 ± 1.2 and 2.75 ± 0.13 U/ml, respectively) inanimals greater than 10 yr of age. Sex differences were significantin the 3- to 4-yr-old animals (male greater than female, P J Clin Endocrinol Metab55: 1198, 1982)

This publication has 12 references indexed in Scilit: