Verlangsamte Sakkaden bei verschiedenen neurologischen Erkrankungen

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Abstract
Four patients suffering from different neurological disorders exhibiting striking slowing down of all saccades are presented. Slow saccades of supranuclear origin are discussed to elucidate whether these eye movements are saccadic at all. Electro-oculographic traces distinguished these particular eye movements and a computer calculated duration, velocity and acceleration identified their saccadic nature. A patient with Wernicke syndrome showed a remarkable improvement of saccadic velocity following thiamine administration. A model of the pathophysiological mechanism is created. The adaptability of the system nearly back to normal in the case of Wernicke syndrome is stressed.

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