Studies on collagen. The changes which collagen undergoes when treated with solutions of hydrochloric acid and sodium hydroxide

Publisher Website
Google Scholar
Abstract
Samples of collagen and the gelatin extracted therefrom, derived from different tissues, were prepared in a highly purified state. Col-lagens treated with NaOH gave on hydrolysis a higher % of diamino-N than those treated with HC1. The swelling of collagen in HC1 and NaOH depended on the previous treatment. Maximum swelling coincided with either a maximum or a minimum of diamino-N. It was concluded that swelling of collagen is accompanied by internal structure changes and scission of closed rings, and that collagen prepared from different tissues has not the same chemical constitution.