Direct Determination of Calcium in Icteric Serum
- 1 June 1963
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 9 (3) , 360-364
- https://doi.org/10.1093/clinchem/9.3.360
Abstract
A rapid method suitable for the direct titrimetric determination of calcium in icteric sera is presented. The major portion of serum chromogens are oxidized to colorless products by either a mixture of hydrogen peroxide and potassium ferricyanide or by sodium hypochlorite. Ethylenediamine tetraacetic acid (EDTA) is the titrant used and either calcein or Cal-Red is suitable as the specific calcium indicator. Results compare favorably with those obtained by the method of Clark and Collip.Keywords
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