Factors Influencing Susceptibility of Nocardia Species to Trimethoprim-Sulfamethoxazole
- 1 April 1978
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 13 (4) , 624-627
- https://doi.org/10.1128/aac.13.4.624
Abstract
Demonstration of synergism between trimethoprim and sulfamethoxazole against 10 Nocardia isolates was found to be critically dependent upon the isolate, the duration of incubation, and the trimethoprim-sulfamethoxazole ratio. Inoculum effect was not significant. The trimethoprim-sulfamethoxazole ratio in the commercial, fixed-dose combination was found to contain too little trimethoprim to be optimal for Nocardia .This publication has 14 references indexed in Scilit:
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