Horn Flies, Stable Flies, and House Flies: Development in Feces of Bovines Treated Orally with Juvenile Hormone Analogues13

Abstract
The development of the horn fly, Hacmatobia irritans (L.), and the stable fly, Stomoxys calcitrans (L.), was inhibited in the feces of cattle treated orally with 1 g/day of the juvenile hormone analogue Hoffmann-La Roche Ro 7-1967 ((E)-4-[(6, 7-epoxy-3-ethyl-7-methyl-2-nonenyl)-oxy]-1,2-(methylenedioxy) benzene (mixed isomers)). Zoecon ZR-515 (isopropyl-11-methoxy-3,7, 11-trimethyl-2,4-dodceadienoate, 57% (E, B) and 33% (Z, E)) was completely effective against stable flies at 100 mg/day and horn flies at 0.7 mg/day. Hoffmann-La Roche Ro 20-3600 ((E)-4-[(6,7-epoxy-3, 7-dimethyl-2-nonenyl)oxy]-1,2-(methylenedioxy) benzene) also inhibited development, but 5 g/day were required. Only ZR-515 and Ro 20-3600 were tested for effect on the house fly, Musca domestica L., and both were ineffective at the doses used. No signs of clinical toxicity were observed in the cattle.

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