The effect of alpha-tocopherol on premenstrual symptomatology: a double-blind study.
- 1 January 1983
- journal article
- other
- Published by Taylor & Francis in Journal of the American College of Nutrition
- Vol. 2 (2) , 115-122
- https://doi.org/10.1080/07315724.1983.10719916
Abstract
In a double-blind, randomized dose-response study, 75 women with benign breast disease were administered a written questionnaire in which they scored the severity of premenstrual syndrome (PMS) symptoms before and after two months of treatment with placebo or alpha-tocopherol (150, 300, or 600 IU/day). Controlling for age and pretreatment scores, alpha-tocopherol had a significantly greater effect than placebo, improving three of the four classes of PMS symptoms. These findings suggest that vitamin E supplementation may be of value in women with severe PMS symptoms.Keywords
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