Simplified Sample Handling Procedure for Monitoring Industrial Isocyanates in Air
- 1 August 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 18 (8) , 384-387
- https://doi.org/10.1093/chromsci/18.8.384
Abstract
Urea derivatives of common isocyanates were formed with N-4-nitrobenzyl-N-n-propylamine (PNBPA) and chromatographed by reversed-phase liquid chromatography. Sample handling and the derivatization procedure were optimized with respect to simplicity, speed, and sensitivity. The resultant procedure is simple, reproducible, and reduces sample handling time from hours to as little as 15 minutes while maintaining detection limits for four common isocyanates below one ppb for a 20 liter air sample.This publication has 0 references indexed in Scilit: