Microbial ωoxylation oftrans-Nerolidol and Structurally Related Sesquiterpenoids
- 1 January 1988
- journal article
- research article
- Published by Taylor & Francis in Biocatalysis
- Vol. 2 (1) , 59-67
- https://doi.org/10.3109/10242428808998180
Abstract
Trans-nerolidol and other related terpenoid compounds varying in configuration and chain length, cis-nerolidol, farnesol, and nerylacetone, were used as substrates in biotransformation reactions. These transformations afforded, among the various metabolites obtained, at least one ω-hydroxylated compound of each respective terpenoid. Aspergillus niger ATCC 9142 and Rhodococcus rubropertinctus DSM 43197, incubated with trans-nerolidol, both gave the 12-hydroxy-trans-nerolidol and the latter, in addition, was further oxidized to the 12-carboxylic acid of trans-nerolidol in fairly good yield.Keywords
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