An Extracellular Substance of Sporothrix Schenckii in Human Infection/Eine extrazelluläre Substanz von Sporothrix schenckii bei menschlichen Infektionen
- 1 September 1983
- Vol. 26 (9) , 462-468
- https://doi.org/10.1111/j.1439-0507.1983.tb03240.x
Abstract
Summary: The ultrastructure of tissue forms of Sporothrix schenckii in human clinical material was described and illustrated by electron micrographs. Such cells were characterized by the presence of an osmiophilic precipitate surrounding the in vivo cell which is believed to represent an antigen‐antibody complex. This substance was not reactive with electron cytochemical modifications of the PAS stain, but appeared to react with a rhodamine antihuman IgG conjugate. No unusual or novel tissue forms were identified in thin sections which might account for the rarity of organisms in biopsy materials from lymphocutaneous disease.Zusammenfassung: Die Ultrastruktur der Gewebeformen von Sporothrix schenckii in menschlichem klinischem Material wird beschrieben und durch Elektronenmikroskopbilder veranschaulicht. Derartige Zellen sind durch das Vorhandensein eines osmiophilen Niederschlages gekennzeichnet, der die Zelle in vivo umgibt und von dem man annimmt, daß er einen Antigen‐Antikörper‐Komplex darstellt. Mit einer ultracytochemischen Modifikation der PAS‐Färbung hat diese Substanz nicht reagiert, wohl aber schien sie mit Rhodamin‐konjugiertem Antihuman‐IgG zu reagieren. An den Ultradünnschnitten wurden keine ungewöhnlichen oder neuartigen Gewebselemente gefunden, welche die Seltenheit der Pilze im Biopsiematerial lymphocutaner Erkrankungen erklären könnte.Keywords
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