Undernutrition and Intestinal Dipeptide Hydrolase Activity in the Rat
- 1 November 1971
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 101 (11) , 1509-1514
- https://doi.org/10.1093/jn/101.11.1509
Abstract
The effects of undernutrition on intestinal mucosal dipeptide hydrolase, alkaline phosphatase, and disaccharidase activities were studied in infant and adult rats. Dipeptide hydrolase activities for glycylproline and valylproline were significantly reduced in undernourished animals at ages 7, 21, 42, and 68 days. The activity of leucylalanine dipeptide hydrolase was not significantly reduced in poorly nourished rats at ages 7, 21, 42, and 68 days, but was reduced at age 115 days. Alkaline phosphatase activity was reduced in undernourished animals at ages 21, 42, and 115 days.Keywords
This publication has 16 references indexed in Scilit:
- Intestinal peptidases.Gut, 1970
- Peptide hydrolase activities of the mucosa of human small intestineJournal of Clinical Investigation, 1969
- Diarrhoea in KwashiorkorBMJ, 1968
- Protein starvation and the small intestine: I. The Growth and Morphology of the Small Intestine in Weanling RatsExperimental and Molecular Pathology, 1968
- INTESTINAL ABSORPTION IN PROTEIN-CALORIE MALNUTRITIONThe Lancet, 1968
- Protein-calorie malnutrition: Effect of deficient diets on enzyme levels of jejunal mucosa of ratsBritish Journal of Nutrition, 1967
- Intestinal Dipeptidases: Dipeptidase Activity in the Mucosa of the Gastrointestinal Tract of the Adult HumanActa Physiologica Scandinavica, 1966
- INTESTINAL BIOPSY IN KWASHIORKORThe Lancet, 1965
- Intestinal dipeptidases I. Spectrophotometric determination and characterization of dipeptidase activity in pig intestinal mucosaBiochimica et Biophysica Acta (BBA) - Enzymology and Biological Oxidation, 1965
- THE TREATMENT AND PREVENTION OF KWASHIORKOR IN FRENCH WEST AFRICAAnnals of the New York Academy of Sciences, 1958