The macular thickness and volume in glaucoma: an analysis in normal and glaucomatous eyes using OCT

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Abstract
Summary: Purpose:  To evaluate macular volume in normal and glaucomatous eyes using Optical Coherence Tomography (OCT).Methods:  Fifty eyes of 30 patients (age: 49–68); 20 eyes normal, 15 eyes with early glaucoma and 15 eyes with advanced glaucoma have been studied with the commercially available OCT unit (OCT 2000) (Humphrey Zeiss, Dublin, CA, USA). All eyes were examined at a scan length of 3.44 mm vertically across the fovea. OCT macular retinal thickness maps were used to calculate macular volume.Results:  We observed significant differences between groups. Normals (7.35 ± 0.455 mm3) and early glaucoma (7.09 ± 0.475 mm3), each had significantly greater volume than subjects with advanced glaucoma (6.678 ± 0.455 mm3).Conclusions:  Volumetric analysis of macular thickness with OCT tomograms may be a useful method of documenting and monitoring patients with early glaucoma and advanced glaucoma. In our analysis, and according to the observations of other authors, OCT macular volumes correlates significantly with glaucoma status.