Transformations of some nickel tetrahydrocorrin tertiary esters
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 21,p. 787-788
- https://doi.org/10.1039/c39770000787
Abstract
LiAlH4 reduction of tertiary ester groups at C–1, C–2, or C–3 in a nickel tetradehydrocorrin results in rapid elimination of the substituent; methylation of the 1-monoester occurs at C–19 and subsequent removal of the ester gives the nickel 1-methyltetradehydrocorrin; rearrangement of the ester group at C–1 to C–2 in neutral nickel tetrahydrocorrins is rapid even at room temperature, and when the product is heated a further rearrangement of the ester to C–3 takes place.This publication has 1 reference indexed in Scilit:
- The methylation process in corrin biosynthesis. Application of 1H{13C} nuclear magnetic resonance difference spectroscopy to a biochemical problemJournal of the Chemical Society, Chemical Communications, 1976