Hypercalciurie-Diagnostik bei Calciumnephrolithiasis

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Abstract
An increased Ca excretion in 24 h urine was found in 32 of 42 out-patients with recurrent calcium nephrolithiasis (Ca excretion > 300 mg in males, > 250 mg in females). Subsequent hospitalization of the 32 patients revealed the following diagnosis after a Ca tolerance test: absorptive hyperc-lciuria in 18, renal hypercalciuria in 18, renal hypercalciuria in 4, primary hyperparathyroidism in 2 and dietary hypercalciuria in 7. Normocalciuria in 10 out-patients was confirmed in 6; in 1 instance there was primary hyperparathyroidism, in 3 there was absorptive hypercalciuria. In 1 patient it was not possible to classify the hypercalciuria. Total as well as nephrogenic cAMP showed wide scatter and was unsuitable in differential diagnosis. In 2 of 3 cases of hyperparathyroidism, the serum level of parathormone was distinctly elevated.
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