Polymer-Supported Bases. 10. Synthesis of Phosphatidylcholines Using Polymer-Supported or Free Acylimidazoles
- 1 March 1989
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 19 (5-6) , 907-915
- https://doi.org/10.1080/00397918908051011
Abstract
Dipalmitoylphosphatidylcholine was synthesized in a good yield by the reaction of L-α-glycerophosphorylcholine with 1-palmitoylimidazole in the presence of DBU. Polymer-supported 1-palmitoylimidazole moiety also could be used as the acylating reagent, though the yield of the choline was moderate.Keywords
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