Storage of Vitamin C by Normal Adults Following a Period of Low Intake

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Abstract
In four cases, the amount of vitamin C necessary to restore the tissues to saturation after a month on a diet very low in vitamin C, ranged from 2200 to 2800 mg., when administered in daily doses of 200 mg. It is suggested that the difference between intake and excretion up to the point of saturation following prolonged deprivation of vitamin C may afford some indication of the maximum vitamin C reserve. On this basis tissue reserves at saturation appear to be of the order of 2500 to 3000 mg. In these experiments, capillary resistance did not give an adequate indication of the state of nutrition with respect to vitamin C.