Studies in terpenoid biosynthesis. Part XVI. Formation of the sesquiterpenoid trichothecin

Abstract
The biosynthetic sequence trichodermol (2)→ 12,13-epoxy-4β,8-dihydroxytrichothec-9-ene (3)→ trichothecolone (4)→ trichothecin (5) in Trichothecium roseum has been established. Earlier evidence suggesting the intervention of crotocin (6) has not been substantiated.

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