Acquired Afibrinogenemia in Pregnancy

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Abstract
ONE of the most catastrophic events in obstetric practice is the occurrence of a fulminating hemorrhagic diathesis usually associated with toxemia of pregnancy and toxic separation of the placenta. Although uncommon, this usually fatal disorder has been encountered by most obstetricians of long experience.1 2 3 For many years it has been suspected that there was a common etiologic background for this hemorrhagic disorder and toxemia of pregnancy, and it has been postulated that the uterus and its contents were the source of a toxic factor.3 4 5 6 In spite of the various theories advanced no toxic substance has actually been identified in the . . .