LATENT EXPRESSION OF A C-GAMMA GENE

  • 1 January 1978
    • journal article
    • research article
    • Vol. 120  (4) , 1160-1163
Abstract
Rabbit 136 represented the 1st instance whereby more than 2 alleles for any immunoglobulin [Ig] locus are detected phenotypically in a single animal. This was reported as the acquisition of the a2 and b6 markers in the animal nominally typed a1a3, b4b5 after intensive immunization. Follow-up studies indicate that another Ig marker, notably d11, also appeared in the postimmune serum. The d11 specificity was detected serologically by the hemagglutination-inhibition assay and chemically by analysis of the CNBr digestion products involving a strategic methionine.