CHANGES IN LUTEINIZING-HORMONE RELEASING HORMONE IN HUMAN-PLACENTA THROUGHOUT PREGNANCY

  • 1 January 1982
    • journal article
    • research article
    • Vol. 60  (4) , 444-449
Abstract
The distribution and content of LH-RH in human placental tissues were detected by enzymatic antibody and immunofluorescence techniques. Anti-LHRH was taken up strongly by cytotrophoblasts and the villous stroma at 8 wk of pregnancy. Anti-LHRH was not taken up at all by syncytiotrophoblasts throughout pregnancy. Apparently, LHRH is synthesized in the cytotrophoblast and villous stroma. The role of placental LHRH in the synthesis of human chorionic gonadotropin is discussed.