Effect of Food on the Bioavailability of Bendroflumethiazide
- 12 January 1978
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 204 (1-6) , 291-293
- https://doi.org/10.1111/j.0954-6820.1978.tb08441.x
Abstract
Bendroflumethiazide (BFT), 10 mg, was given orally to 8 subjects after fasting overnight and together with a meal. Concentrations of the diuretic in plasma and urine were determined by GLC. As judged by AUC.infin. [area under the plasma concentration time curve] and urinary recovery of BFT, the bioavailability of the diuretic was not influenced by concomitant intake of a meal.Keywords
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