No Association of Known Dr Antigens with Ankylosing Spondylitis
- 30 March 1978
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 298 (13) , 744-745
- https://doi.org/10.1056/nejm197803302981317
Abstract
To the Editor: Because the 90 per cent frequency of HLA-B27 in whites with ankylosing spondylitis (AS) declines significantly in other populations with AS (75 per cent in non-Ashkenazi Jews,1 67 per cent in Japanese2 and 48 per cent in American blacks3), it was hoped that the newly described B-cell alloantigens, now referred to as DR antigens, would provide a unifying feature for AS irrespective of race and irrespective of whether B27 was positive or negative. We examined this possibility in 22 patients with classic AS, using the 180 DR antiserums of the Oxford Workshop, which define seven new . . .Keywords
This publication has 1 reference indexed in Scilit:
- Human Lymphocyte Antigen, HL–A27, in Japanese Patients with Ankylosing SpondylitisTissue Antigens, 1975