Hydrazinium Monoformate: A New Hydrogen Donor. Selective Reduction of Nitrocompounds Catalyzed by Commercial Zinc Dust
- 1 March 2003
- journal article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 33 (2) , 281-289
- https://doi.org/10.1081/scc-120015713
Abstract
The nitro group in aliphatic and aromatic nitro compounds also containing reducible substituents such as ethene, nitrile, acid, phenol, halogen, ester, etc., are selectively and rapidly reduced at room temperature to corresponding amines in good yields by employing hydrazinium monoformate, in the presence of commercial zinc dust. It was observed that, hydrazinium monoformate is more effective than hydrazine or formic acid and reduction of nitro group occurs without hydrogenolysis in the low cost zinc dust compared to expensive metals like palladium.Keywords
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