THE INHIBITION BY PROGESTERONE OF UTERINE EPITHELIAL PROLIFERATION IN THE MOUSE

1 June 1973

journal article
Published by Bioscientifica in Journal of Endocrinology

Vol. 57 (3) , 549-554
https://doi.org/10.1677/joe.0.0570549

Abstract

Progesterone given at the same time as oestradiol-17β prevented approximately 40% of uterine luminal epithelial cells from entering DNA synthesis, but did not prolong the G₁, S or G₂ phases in the remainder. However, it blocked the entry of these cells into a second round of DNA synthesis. It is suggested that uterine luminal epithelial cells are only sensitive to progesterone for a limited period in G₁.

Keywords

PROGESTERONE
PROLONG
OESTRADIOL
UTERINE
SUMMARY
EPITHELIAL
BLOCKED
ROUND
17Β

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