Selective Enzymatic Removal of Protecting Functions: Heptyl Esters as Carboxy Protecting Groups in Glycopeptide Synthesis
- 1 January 1992
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1992 (01) , 39-40
- https://doi.org/10.1055/s-1992-21258
Abstract
The selective C-terminal deprotection of acid- and base-labile multifunctional O-glycopeptide heptyl (Hep) esters is achieved under mild conditions (pH 7; 37 °C) by enzymatic hydrolysis with a lipase from Mucor javanicus.Keywords
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