Superselective intracerebral chemotherapy of malignant tumours with BCNU
- 1 March 1986
- journal article
- research article
- Published by Springer Nature in Neuroradiology
- Vol. 28 (2) , 118-125
- https://doi.org/10.1007/bf00327882
Abstract
Early experience shows that: 1. Superselective intra-arterial catheterization above the ophthalmic artery minimizes the orbital complications. 2. Catheterization in a distal branch may lead to the non-infusion of a part of the tumor territory. 3. A much higher concentration of the drug is achieved by superselective intra-arterial infusion than by intravenous injection. 4. Longer infusions seem more efficacious than bolus injection. 5. Early trapping of the drug appears to be essential for therapeutic efficacy.Keywords
This publication has 35 references indexed in Scilit:
- Intra-arterial BCNU chemotherapy for treatment of malignant gliomas of the central nervous systemJournal of Neurosurgery, 1984
- Intra-arterial ACNU therapy for malignant brain tumorsJournal of Neurosurgery, 1983
- Ocular Toxicity Associated With High-Dose CarmustineArchives of Ophthalmology (1950), 1982
- Aspirin and systemic heparinization in diagnostic and interventional neuroradiologyAmerican Journal of Roentgenology, 1982
- Two different calibrated-leak balloons: experimental work and application in humans.1982
- Blood-brain barrier: phenomenon of increasing importance to the imaging clinicianAmerican Journal of Roentgenology, 1982
- Is There a Therapeutic Role for Blood-Brain Barrier Disruption?Annals of Internal Medicine, 1980
- Intra-arterial BCNU therapy in the treatment of metastatic brain tumor from lung carcinoma.A preliminary reportCancer, 1979
- Drug entry into the brainBrain Research, 1979
- Intra‐arterial vincristine therapy of primary gliomasCancer, 1965