New Improved Reagents for the Asymmetric Allylation of Ketones

Abstract
The synthesis of new 1,2-aminoalcohol derivatives 1b-d and 8a-h and their application in the stereoselective allylation of ethyl methyl ketones is described. The best results were obtained with the biphenyl derivative 8f, allowing the synthesis of tert-homoallylic ether 9f and 10f with a selectivity of 18:1.

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