Gamma Scintigraphy Using Tc-99m Labeled Antibody to Human Chorionic Gonadotropin

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Abstract
A case report is presented describing a 27 yr old woman with invasive trophoblastic hydatidiform mole metastatic to the lung. Gamma scintiscanning, using a polyclonal and monoclonal antibody specific to human chorionic gonadotropin, hCG, and labeled with 99mTc, is described. The area of the primary lesion in the uterus was demonstrated with both antibodies tested without computer subtraction techniques; metastatic deposits in the lung were detected only with the aid of blood pool subtraction techniques.