Convenient Biological Assay for Polyethylene Glycol-Interferons in Patients with Hepatitis C
Open Access
- 1 September 2004
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 48 (9) , 3610-3612
- https://doi.org/10.1128/aac.48.9.3610-3612.2004
Abstract
The vesicular stomatitis virus cytopathic effect reduction assay is suitable to quantify polyethylene glycol-alpha interferon 2a (PEG-IFN-α2a) and PEG-IFN-α2b. Human serum and ribavirin did not interfere with the assay. This bioassay was successfully used for assaying PEG-IFN-α2a and PEG-IFN-α2b in serum samples from patients undergoing combination therapy.Keywords
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