CHANGES IN TOTAL BODY CHLORIDE DURING GROWTH

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Abstract
Total body content of chloride has been estimated in a series of infants and young adults by the method of radiobromide dilution. Results obtained by this method compare favorably with those reported for direct chemical analysis. Total body content of chloride is approximately 50 mEq./kg. body weight in young infants, 43 mEq./kg. in older infants, and 26 to 33 mEq./kg. in adults. Changes in chloride content occurring during growth can be described by the use of the differential growth equation, which states that chloride content is a simple power function of body weight. The similarity between the differential growth constants for sodium and chloride is noted.

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