Height and weight in children with vesicoureteric reflux and renal scarring

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Abstract
Height standard deviation scores (HSDS) and weight-for-height index (WHI) at diagnosis were evaluated in 156 children aged 2 months to 10.8 years (mean 3.7 years) with vesicoureteric reflux (VUR) and normal creatinine clearance, and in 156 age- and sex-matched healthy controls. Forty-three patients had bilateral VUR with scintigraphic signs of renal scarring (B SCAR+), 25 had bilateral VUR without renal scarring (B SCAR−); 40 had unilateral VUR with (U SCAR+) and 48 unilateral VUR without (U SCAR−) renal scarring. B SCAR+ patients had an average HSDS of −0.5±1.4 (SD) which was significantly (P=0.02) below that of controls (0.05±1 HSDS) and an average WHI of 100.6%±16% which was significantly (P=0.007) below that of controls (108%±12%); 14% of B SCAR+ patients had a height below −2 HSDS. B SCAR−, U SCAR+, and U SCAR− patients had heights near to O HSDS which was not different from that of controls, as well as WHI between 104% and 107.9%, which was not different from that of controls. HSDS and WHI were significantly (P=0.00001) correlated in patients but not in controls. B SCAR−, U SCAR+, and U SCAR− patients are similar to healthy controls in weight and in height growth and have, on average, some excess weight as do the latter. In contrast, B SCAR+ subjects have a significant decrease of the relative height and normal WHI.