Hemostatic Effects of Heterologous Platelets in Thrombocytopenic Rats.

1 October 1962

journal article
research article
Published by Frontiers Media SA in Experimental Biology and Medicine

Vol. 111 (1) , 15-18
https://doi.org/10.3181/00379727-111-27692

Abstract

Fresh human platelets transfused into thrombocytopenic rats are removed from the circulation within 2 to 3 hours. The output of red blood cells into the lymph is reduced (-70%) despite the declining platelet count. The effects of fresh rat platelets are both more marked and more consistent. Species-specificity may perhaps account for the lesser activity of heterologous platelets.

Keywords

LYMPH
RADIATION EFFECTS
THROMBOPENIA