BILE PIGMENT FORMATION IN THE LIVER FROM HEMOGLOBIN

1 July 1931

journal article
research article
Published by American Physiological Society in American Journal of Physiology-Legacy Content

Vol. 97 (4) , 654-657
https://doi.org/10.1152/ajplegacy.1931.97.4.654

Abstract

[long dash]In experiments on [male] bullfrogs (no. not stated) suitable perfusion with dilute Hb solution was followed by bile pigment formation and elimination, proving that Hb is converted into bile pigment in the liver. Perfusion of Hb through the hepatic artery led to bile pigment formation but not perfusion through the portal vein. The appearance of bile pigment in the cystic duct after perfusion with Hb was inhibited by HCN.

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