Absence of Regeneration in the Spinal Cord of the Young Rat

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Abstract
Using a total of 102 albino rats, age 30 to 40 days, spinal cord transections were performed. In one group of 40 animals fresh autogenous sciatic nerve grafts were inserted between the cut ends of the spinal cord. In 41 animals a pre-degenerated sciatic nerve graft was interposed, and in an additional 21 animals no interposition was made between the cut ends of the spinal cord. Most of their animals were sacrificed when moribund as a result of urinary infection. Autopsies were performed 10 days, 30 days, 60 days, 120 days, 180 days, 240 days, 400 days following the operation. In no case was either functional or anatomical evidence of regeneration of the spinal cord observed.
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