Glycolipid and Mucopolysaccharide Abnormality in Fibroblasts of Fabry's Disease
- 27 June 1969
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 164 (3887) , 1522-1523
- https://doi.org/10.1126/science.164.3887.1522
Abstract
Cultures of skin fiibroblasts from a patient with Fabry's disease showed an accumulation of the glycolipid, galactosyl-galactosyl-glucosyl ceramide. Such cells also showed metachromasia on staining with toluidine blue and a markedly elevated acid mucopolysaccharide content.Keywords
This publication has 10 references indexed in Scilit:
- Fabry's Disease: Classification as a Sphingolipidosis and Partial Characterization of a Novel GlycolipidPublished by Elsevier ,2021
- Concentrations of glycosyl ceramides in plasma and red cells in Fabry's disease, a glycolipid lipidosisJournal of Lipid Research, 1969
- Acid mucopolysaccharides in cultured fibroblasts of cystic fibrosis of the pancreasBiochemical and Biophysical Research Communications, 1968
- Gaucher's Disease: A Genetic Disease Detected in Skin Fibroblast CulturesScience, 1968
- SUBCELLUAR SITES FOR SYNTHESIS OF CHONDROMUCOPROTEIN OF CARTILAGEThe Journal of cell biology, 1968
- The accumulation of hyaluronic acid in cultured fibroblasts of the Marfan syndromeBiochemical and Biophysical Research Communications, 1968
- A GENETIC CELL MARKER IN CYSTIC FIBROSIS OF THE PANCREASThe Lancet, 1968
- Quantitative determination of the neutral glycosyl ceramides in human bloodJournal of Lipid Research, 1967
- Enzymatic Defect in Fabry's DiseaseNew England Journal of Medicine, 1967
- Hurler's syndrome: biosynthesis of acid mucopolysaccharides in tissue culture.Proceedings of the National Academy of Sciences, 1966