Hairy cell leukemia in three siblings: An apparent HLA-linked disease
- 1 February 1982
- Vol. 49 (3) , 538-542
- https://doi.org/10.1002/1097-0142(19820201)49:3<538::aid-cncr2820490323>3.0.co;2-6
Abstract
In a sibship of 11 adults the HLA haplotype A1, B7 occurred in four brothers, three of whom developed hairy cell leukemia (HCL) within a seven-year period. While this haplotype does not appear to occur with increased frequency in random cases of HCL, the fact that three cases of this uncommon and unique disorder occurred within one family and affected siblings with a common haplotype strongly suggests a genetic linkage.This publication has 17 references indexed in Scilit:
- Hairy Cell Leukemia-Associated Familial Lymphoproliferative DisorderAnnals of Internal Medicine, 1979
- Microdroplet Testing for HLA-A, -B, -C, and -D Antigens: The Philip Levine Award LectureAmerican Journal of Clinical Pathology, 1978
- Multiple Sclerosis and High Incidence of a B Lymphocyte AntigenScience, 1976
- SPECIFIC B-CELL ANTIGENS ASSOCIATED WITH GLUTEN-SENSITIVE ENTEROPATHY AND DERMATITIS HERPETIFORMISThe Lancet, 1976
- Genetic association of multiple sclerosis and HL‐A determinantsNeurology, 1976
- Varied manifestations of a familial lymphoproliferative disorderThe American Journal of Medicine, 1975
- HL-A-Linked Human Immune-Response GenesProceedings of the National Academy of Sciences, 1973
- HL‐A Antigens and Multiple SclerosisTissue Antigens, 1972
- Multiple Sclerosis: Association with HL—A3Tissue Antigens, 1972
- Lymphoreticular malignancies and immunologic abnormalities in a sibshipThe American Journal of Medicine, 1971