Reconstruction of Intact γ-Globulin from S-Sulfonated γ-Globulin In Vivo

1 June 1976

journal article
research article
Published by Oxford University Press (OUP) in The Journal of Biochemistry

Vol. 79 (6) , 1377-1379
https://doi.org/10.1093/oxfordjournals.jbchem.a131192

Abstract

The conversion of the S-surfonate group in a peptide to a disulfide bond has been observed in vitro. This paper reports that the conversion of this group in human S-sulfonated γ-globulin (S-GG) appeared to occur in vivo judging from the change in molecular weight of S-GG observed in the presence of sodium dodecyl sulfate (SDS) and the restoration of hemolytic activity.

This publication has 1 reference indexed in Scilit:

Studies on the Synthesis of Insulin from Natural and Synthetic A and B Chains. I. Splitting of Insulin and Isolation of the S-Sulfonated Derivatives of the A and B Chains^*
Biochemistry, 1967