Treatment of Retinoblastoma by Radiation and Triethylenemelamine

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Abstract
We have been treating retinoblastoma by radiation according to a method described by us first in 1936.1 The technique, which was devised by Dr. Hayes E. Martin, Memorial Center for Cancer and Allied Diseases, includes the employment of special cones at a temporal and a nasal portal in an effort to deliver an adequate dose to the posterior sector of the eye, to the exclusion of the vulnerable anterior sector. Subsequent reports on the use of this technique were made in 1942,2 1945,3 and 1949.4 The treatment is employed for patients with bilateral tumors whose eye with the more advanced disease has been enucleated. The less involved eye has been treated when it was thought that useful vision might be salvaged if the tumor could be arrested. Since the institution of the treatment in 1936,1 a total of 148 patients have been treated. Forty-three patients

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